1) Peyton Manning vs. MIN
Minnesota's top cover CB, Xavier Rhodes, sustained a concussion and shoulder injury last week. Look for Manning to throw at Demaryius Thomas, the less than 100% Rhodes's most likely cover assignment. Despite having one of the Top 10 Overall Pass Defenses, Minnesota hasn't played an elite QB-WR duo this season. Perhaps the Vikings toughest QB-WR duo faced, was Detroit's Matthew Stafford (ranked #15 QB by ESPN) and Calvin Johnson (ranked #6 WR by ESPN). In the end, the two posted solid numbers, Stafford 19 fantasy points and Johnson 14 fantasy points against the Vikings's pass defense.
2) Andy Dalton vs. KC
Dalton is a force to be recked with in 2015 for the Red Rifle averages 23 points per game, third best in the league. Dalton hasn't played elite pass defenses, but nonetheless performed well against solid to good defenses (SD #12, BAL #16, and OAK #21).
On the other side of the ball, in 2015, Kansas City allows around 3 TDs, 287 yards or about 25 fantasy points, per game. On CBS and ESPN's, the Chiefs defense is one of the most dropped for Week 4. On the flip side, KC's defense faced Peyton Manning in Week 2 (ranked #4 QB by ESPN) and Aaron Rodgers (ranked #1 QB by ESPN) in Week 3.
3) David Carr vs. CHI
Chicago restructured their secondary in the off season, bringing in the 3x Pro Bowler Antrel Rolle (SS), Alan Ball (the CB has spent most of his 9 year career as a back up DB), and rookie, Adrian Amos (FS) to join second year cornerback, Kyle Fuller as the only returning starter to the Bears secondary. Not to anyone's surprise, the pass defense has suffered, allowing a passer rating of 123.8 and 18.5 fantasy points a game.
This Sunday, Chicago will meet David Carr, the second year QB, who's on pace for 26 TDs, 5 INTs, and 3,872 passing yards, currently ranks 12th for QB fantasy football points, averaging 16 points per game. Over the last two games, Carr's posted 23 points per games, racking up over 300 yards per game and at least 2 TD passes.